WebCISH / SOCS Protein LS-G24821 is a Recombinant Human CISH / SOCS produced in E. coli aa 1-258 with His-T7 tag(s). Price. Catalog Number. $249. LS-G24821-10. Unit Size … WebAbstract The cytokine-inducible SH2 domain containing protein (CISH) is the founding member of the suppressor of cytokine signaling (SOCS) family of negative feedback …
Cytokine-inducible SH2 domain containing protein contributes to ...
WebOct 4, 2024 · Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB). Targeting CISH … WebJun 10, 2010 · Cis, the protein product of Cish, has an Src homology 2 (SH2) domain in the middle of its sole structural motif. Uchida et al. (1997) isolated a human CISH cDNA. The … in angle\u0027s class ii div 2 occlusion there is
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WebCytokine-inducible SH2-containing protein (CISH) involved in regulating metabolism, the expansion of intestinal tuft cells and type-2 innate lymphoid cells, and ageing-related airway inflammation. Here, we investigated the role of CISH in ageing-related colitis susceptibility. The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be … See more Cytokine-inducible SH2-containing protein is a protein that in humans is encoded by the CISH gene. CISH orthologs have been identified in most mammals with sequenced genomes. CISH controls T cell receptor (TCR) signaling, … See more Model organisms have been used in the study of CISH function. A conditional knockout mouse line, called Cish was generated as part of the International Knockout Mouse Consortium See more • Human CISH genome location and CISH gene details page in the UCSC Genome Browser. See more CISH has been shown to interact with IL2RB and Growth hormone receptor. and PLCG1. See more • Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ (May 2002). "The SOCS box: a tale of destruction and degradation". Trends in Biochemical … See more WebThe cytokine-inducible Src homology 2-containing protein (CISH) is an endogenous suppressors of signal transduction and activator of transcription (STAT) and acts as a key negative regulator of inflammatory cytokine responses. Downregulation of CISH has been reported to associate with increased activation of STAT and enhanced inflammatory … in andy griffith what happened to opie\u0027s mom